They've ruined everything! Welcome to WatchMojo, and today we’re counting down our picks for TV characters that have become hard to root for given the real-life controversies of the actors who played them.

Time for an appointment at Seattle Grace. For this list, we’re looking at the most memorable from "Grey's Anatomy's" expansive line-up of characters. Hospitals would not exist without patients, but this list will focus exclusively on the staff - so you won’t see characters like Denny Duquette. Our list includes Izzie Stevens, Callie Torres, Mark Sloan, Alex Karev, Miranda Bailey and more! Join MsMojo as we count down our picks for the Top 10 Best Grey’s Anatomy Characters.

From failed adaptations to canceled projects, Warner Bros has left a trail of disappointment for DC fans. Join us as we count down our picks for the DC characters who suffered the most under Warner Bros' handling! These beloved heroes and villains deserved better than what they got in their big screen adaptations.

Hollywood's obsession with live-action remakes continues to disappoint! Join us as we explore the most regrettable adaptations of beloved animated characters. From soulless CGI animals to misunderstood iconic personalities, these transformations left fans wishing studios had just left well enough alone.

Get ready to feel your blood boil as we count down cinema's most loathsome personalities! From manipulative villains to insufferable heroes, these characters make us want to throw popcorn at the screen. Whether they're backstabbing friends, ruining lives, or just being plain cruel, these film figures have earned our collective hatred.

Who would you trust to come to your rescue? In this countdown, we're spotlighting animated Disney characters we’d feel safest calling in a pinch. From steadfast friends and dedicated parents to multitasking heroes, these are the folks we know would step up if things went wrong. Which Disney character would you dial first in an emergency situation?

Some TV characters just get under our skin no matter how much screen time they get. From annoying quirks and poor decisions to toxic behavior and self-centered attitudes, these main characters have tested our patience in unforgettable ways. Join us as we dive into the most intolerable protagonists who left viewers frustrated, questioning why they were ever given the spotlight.

From talking towels to Christmas miracles, South Park has given us countless memorable characters who've faded into the background. Join us as we look back at some of the show's most underappreciated personalities who deserve another moment in the spotlight!

Dive into the world of cinema's most nuanced and compelling female characters! We're exploring the women who defy stereotypes, challenge expectations, and bring incredible depth to the big screen. From complex protagonists to unforgettable anti-heroines, these characters are anything but one-dimensional.

From stalkers disguised as romantic leads to manipulative bad boys with pretty faces, let's examine the problematic male characters that viewers can't help but love. Despite their toxic traits, these characters continue to captivate audiences through their charm, good looks, and tragic backstories.

From bartenders to billionaires, Springfield's most memorable residents weren't created in a vacuum! Join us as we explore the fascinating real-life inspirations behind your favorite yellow-skinned characters. From Hollywood legends to local personalities, these origin stories will change how you watch the show forever!

From magical mentors to loyal friends, the Marvel Cinematic Universe is filled with incredible supporting characters who deserve their moment in the spotlight. Join us as we celebrate the heroes who may not always get top billing, but definitely steal the show whenever they appear on screen!

From beloved cartoon characters to live-action nightmares! Join us as we explore the most disappointing CGI adaptations that left fans wishing for their 2D versions back. From questionable design choices to uncanny valley territory, these digital makeovers sparked major backlash from devoted audiences.

Give these characters a second glance! Welcome to WatchMojo, and today we’re counting down our picks for the fantasy movie characters that we feel deserve more love and attention.

From vampiric charmers to controversial antagonists, these gaming characters set the internet ablaze! Join us as we explore the digital personalities that dominated social media, sparked heated debates, and created unforgettable gaming moments. Which character's impact surprised you the most?