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VOICE OVER: Phoebe de Jeu WRITTEN BY: Jesse Singer
These Penny and Sheldon moments on "The Big Bang Theory" are #FriendshipGoals. Our countdown includes the first "Soft Kitty," the love test, the flash drive, and more!

#10: The First “Soft Kitty” "The Pancake Batter Anomaly"

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Top 20 Penny & Sheldon Moments on The Big Bang Theory

The “Soft Kitty” song would become something very special between Penny and Sheldon and in the season one episode, “The Pancake Batter Anomaly" we got to hear it for the very first time. This was still very early on in their relationship, and Sheldon was being the selfish jerk he always is when he’s sick, and yet, Penny still took care of him. Singing “Soft Kitty” and rubbing Vaporub counter-clockwise on someone's chest can be quite the bonding moment between two people, as it was in this case for Sheldon and Penny.

#9: Picking Out a Suit "The Pants Alternative"

In season one, she helped Leonard pick out a suit to wear for a conference and in season three Penny took Sheldon shopping for a suit to wear to his award ceremony. The montage that follows is a wonderful Sheldon and Penny moment as his choices get more and more ridiculous until he finally tries on the simple black suit that she suggested. Her amazed and slightly breathless reaction when Shelly walks out of the changing room, looking all dapper, is almost as good as his reaction to Amy’s wedding dress many years later. Although, can we all agree that she was wrong about the checkered suit he tried on? That one looked great also, right?

#8: The Love Test "The Intimacy Acceleration"

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It could be argued that the evolution of Sheldon and Penny’s relationship, and their understanding and appreciation of each other over the course of the series is the most important relationship on the show. Throughout the sitcom’s run, there are some key moments that are signposts of that growth and evolution, with the love test being one of them. And while they didn’t fall in love after doing the test, they did fall deeper “in like.” But did they end up going to GaryCon together? That’s what we want to know.

#7: The Scavenger Hunt "The Scavenger Vortex"

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Top 10 Funniest Penny Moments on The Big Bang Theory

If you were looking for the 7th best Penny and Sheldon moment, all the clues and a riddle would point to Team Community College Night School from "The Scavenger Vortex" episode in season seven. Penny’s street smarts combined with Sheldon’s book smarts, and his bowling ball, made The Lightning Sharks an almost unbeatable team. We say “almost” because Raj made sure there were no losers. Which leads us to maybe the most important question of the entire episode… how did he get the gold coins in everyone’s pockets without them knowing?

#6: Birthday Bathroom "The Celebration Experimentation"

When Sheldon gets overwhelmed at his party and runs to the bathroom to escape, it’s Penny who goes to talk to him. And while in that moment, it makes perfect sense for her to be that person, she acknowledges how she used to be the person that would have been making fun of Sheldon rather than comforting him. Sheldon loves Amy and Leonard is his best friend, but the birthday bathroom scene is a nice example of the special relationship he has with Penny - and how it, and they, changed over the years.

#5: Penny Blossoms "The Work Song Nanocluster"

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Top 10 Penny & Leonard Moments on The Big Bang Theory

In an attempt to earn extra money, Penny starts a business making flower hair barrettes she calls “Penny Blossoms.” When she shows Sheldon what she’s doing, he does some quick math and points out that her hard work is only going to make her $2600 a year. Disappointed by that figure, Penny asks Sheldon for help, which he does by creating an assembly line process and teaching her some production-improving sea shanties. For her part, Penny introduces Sheldon to caffeine, and although she does get some orders and makes some money that first day, we never hear about the Penny Blossoms again.

#4: Emergency Room "The Adhesive Duck Deficiency"

When Penny falls in the bathtub, Sheldon takes on the role of the hero and drives her to the emergency room. While the drive there is in itself a great moment between these two, the scene in the emergency room with them filling out the paperwork is truly a top Penny and Sheldon interaction. Especially when she begs him to be sympathetic, but his efforts just come across as more creepy than comforting. Then we get back to the apartment and in a truly great turn-about-is-fair-play moment, Penny asks Sheldon to sing her “Soft Kitty.”

#3: The Flash Drive "The Terminator Decoupling"

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When the guys head to San Francisco on a train and Sheldon forgets a flash drive with his paper on it at home, Penny is his only hope of retrieving that paper. So, Sheldon calls Penny, asks her very nicely to do him a favor and Penny gets him the paper he needed. Bazinga! You fell for another one of our classic pranks. In actuality, Sheldon doesn’t ask nicely, Penny messes with him a little and Leonard has to grab the phone and do a little mediating between them. But we weren’t joking when we said Penny got Sheldon that all important paper.

#2: Solving String Theory "The Solo Oscillation"

Sometimes it just takes a new set of eyes to solve a problem. And in this case, those eyes belonged to Penny and that problem was string theory. While she usually tunes out when any of the guys are talking science, this night she actually remains focused and awake as Sheldon explains string theory to her. And with one simple word, “knots,” she opens Sheldon’s eyes to amazing possibilities that he hadn’t ever considered. And the best part of all is when she tells Leonard and Amy about it. The stunned look on their faces is priceless. Before we unveil our top pick, here are a few honorable mentions. Riding the Elevator Together, “The Change Constant” The More Things Change, the More They Stay the Same Penny Quits Her Job, "The Occupation Recalibration" Sheldon Can Be Understanding & Supportive, Even Without Lemonade "A Streetcar Named Desire," "The Monster Isolation" Sheldon Doesn’t Need His Electronics to Enjoy Penny’s Performance When Leonard Is at Sea, "The Hofstadter Insufficiency" Sheldon & Penny Have a Moment of Revelations & Another Hug The Chair, "The Infestation Hypothesis" No Snickerdoodles & a Dirty Chair: A Lose-Lose for Sheldon

#1: The Nimoy Napkin Hug "The Bath Item Gift Hypothesis"

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Top 10 Big Bang Theory Moments - Best of WatchMojo

There’s a reason why this moment gets mentioned so often in almost any discussion of “The Big Bang Theory” moments. It’s because it really is that great. The fact that Penny thought of getting Sheldon this gift is super sweet, but we can probably all admit that we’re more impressed by the fact that she recognized Leonard Nimoy and knew who he was in the first place. Then there’s Sheldon’s overwhelmed reaction, which is not only amazing, but it also brings us to the hug! It’s a display of affection that, even in season two, we could all recognize for just how special it was.

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