Top 10 Times The Big Bang Theory Cast Couldn't Keep a Straight Face

In Season Nine, Stuart invites the girls over to the comic book store to get their advice on how to bring more women through the door. When asked what he’s done so far, he mentions the “breastfeeding area” and tries to allay their concerns by telling them about the camera he had installed above them. In the episode that aired, this last comment creeps the girls out. However, in a great blooper, actor Kevin Sussman (who plays Stuart) can’t quite make it through his speech which ends up cracking up the rest of the cast in the scene as well.

Okay, so we have to admit that Sheldon handing Wil Wheaton a Wesley Crusher action figure and telling him to “feel free to play with yourself” - now that’s a great line. It still makes us laugh every time we watch that episode. And it turns out, Mayim Bialik liked it also. So much so in fact that the actress just couldn’t stay in character when it was her time to speak next. She was supposed to be angry - which we see in the aired episode - but in the blooper, she couldn’t even get started.

Depending on your POV feet can be sexy or gross, but not many people find them funny. However, watching Kaley Cuoco go to town on her feet in this season four scene was too much for Simon Helberg to handle. As we saw in the scene that made it to air, Howard is supposed to admonish Penny for scrubbing her feet wrong and then take over and show her how it's done. But in this take that ended up on the blooper reel, Helberg - although he tries hard to hang in there - can’t help but break as Penny scrubs and scrubs and scrubs away.

In Season Six, Raj had the very funny idea of dressing up as Indiana Jones’ mocha-skinned love child ‘Indian Jones’ for Halloween. The problem is that Jim Parsons and Simon Helberg thought it was a really funny idea also. This was a problem because every time Kunal Nayyar would try and get his lines out, those other two would keep cracking up. And if that wasn’t bad enough, once Parsons and Helberg were able to hold it together and keep a straight face, Nayyar just couldn’t get the line out properly for take after take after take after…..

One of the things that makes this scene so funny is how long Helberg and Nayyar hold their positions with their faces just a couple of inches from each other. If you’re wondering how they managed to do it without laughing, well the answer is… they didn’t. At least not on the first take. We’re not sure how many takes they did, but we do know that at least one of them led to this great blooper in which they hold, hold, and hold, but eventually Nayyar cracks a smile. Helberg manages to hang on a bit longer, but not by much.

In the Season Nine episode “The Fermentation Bifurcation,” the gang runs into Penny’s ex Zack at a wine tasting and gets to talking about science. Because, as Zack points out, he loves science and can even name a number of famous scientists including Mike deGrasse Tyson. Zack’s name mixup gets a smile of superiority from the geniuses - as the script certainly called for. What it didn’t call for though, was Kaley Cuoco bursting out laughing - which she did during one of the takes when Zack stumbles over the name mixup.

Raj might just be the character most in touch with his feelings and the best one to give advice to the couples in the group. But that doesn’t mean they always want his advice. And in “The Discovery Dissipation” each couple, one after the other, tells him exactly that. First, it's Howard and Bernadette, followed by Sheldon and Amy. But before they got a good take of Amy telling Raj to leave, there were a couple in which neither Nayyar, Bialik nor Parsons could keep a straight face as Raj doled out his relationship advice.

Howard is a master of impressions and in Season Six’s “The Love Spell Potential,” we got to enjoy a number of them - from Nicolas Cage to Christopher Walken. But when the girls return to the apartment where the guys are playing Dungeons and Dragons, Howard breaks out his Al Pacino impression to invite them to join in on the game. And yes, the characters are supposed to appreciate the impression, but if you look at the cast around Howard, you can see that these are real laughs - not acting laughing.

The episode in which Sheldon takes care of a sick Amy is filled with some of the biggest laughs of the series. We all remember Sheldon putting VapoRub on Amy’s chest and spanking her to “punish” her for lying about being sick once her condition had improved. Well, as big as the laughs from the studio audience were during these scenes, so too were Parsons and Bialik’s character breaks in the bloopers for each one. Bialik actually goes and winks at Parsons while he rubs her chest and Parsons loses it after each spank of her rear end.

It often requires multiple takes to get a scene right, and actors can break character numerous times before finally keeping a straight face for the scene that makes it into the episode. And then there are times when the scene that makes it to air isn’t the one where they don’t break, but rather the one in which they break the least. Case in point, Howard and Raj’s concert at the comic book store in Season Nine. As you can see in this blooper, Kaley Cuoco is breaking through pretty much the entire song. But check out the actual scene and you’ll see Cuoco holding strong when they first cut to her, but once Nayyar and Helberg hit those high notes, she breaks yet again.